Histone chaperone ASF1A is required for maintenance of pluripotency and cellular reprogramming
- 15 August 2014
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 345 (6198), 822-825
- https://doi.org/10.1126/science.1254745
Abstract
Factor in oocyte assists reprogramming: Unfertilized eggs contain components that can dedifferentiate other cells that have gone down the path toward a specific cell fate. Gonzalez-Muñoz et al. show that the protein-folding factor ASF1A facilitates this reprogramming event and it acts at a particular phase of germ cell division termed metaphase II. ASF1A helps turn differentiated cells such as human adult dermal fibroblasts into undifferentiated pluripotent stem cells. Science , this issue p. 822This publication has 34 references indexed in Scilit:
- Nuclear Wave1 Is Required for Reprogramming Transcription in Oocytes and for Normal DevelopmentScience, 2013
- Epigenetic memory in induced pluripotent stem cellsNature, 2010
- Direct cell reprogramming is a stochastic process amenable to accelerationNature, 2009
- A gene expression signature shared by human mature oocytes and embryonic stem cellsBMC Genomics, 2009
- The histone chaperone Asf1 at the crossroads of chromatin and DNA checkpoint pathwaysChromosoma, 2006
- The transcriptome of human oocytesProceedings of the National Academy of Sciences of the United States of America, 2006
- Equivalency of Nuclear Transfer‐Derived Embryonic Stem Cells to Those Derived from Fertilized Mouse BlastocystsThe International Journal of Cell Cloning, 2006
- Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined FactorsCell, 2006
- Two New S-Phase-Specific Genes fromSaccharomyces cerevisiaeYeast, 1997
- Viable offspring derived from fetal and adult mammalian cellsNature, 1997