Functional Capacity of Colostral Leukocytes from Women Delivering Prematurely
- 1 January 1989
- journal article
- research article
- Published by Wiley in Journal of Pediatric Gastroenterology and Nutrition
- Vol. 8 (1), 89-94
- https://doi.org/10.1097/00005176-198901000-00017
Abstract
The phagocytic, bactericidal, and metabolic activity of colostral leukocytes from mothers delivering preterm infants was compared with that of colostral leukocytes from mothers of term infants. In addition, the proliferative capacity of colostral lymphocytes was compared. Preterm adherent colostral leukocytes had a significantly higher phagocytic index than term colostral adherent leukocytes. Mean ± SEM values were 5.4 ± 0.5 versus 2.7 ± 0.2, respectively (p < 0.001). Bactericidal capacity against Escherichia coli and nitroblue tetrazolium reduction of preterm and term colostral leukocytes were comparable. Lymphocyte proliferative response was equivalent in preterm and term milk. We conclude that colostral leukocytes from preterm mothers are at least as functional in their antimicrobial activity and possibly phagocytose even better than the colostral cells of mothers of term infants.This publication has 3 references indexed in Scilit:
- Oxidative metabolic response and microbicidal activity of human milk macrophages: effect of lipopolysaccharide and muramyl dipeptideInfection and Immunity, 1985
- Different maturation of neutrophil chemotaxis in term and preterm newborn infantsThe Journal of Pediatrics, 1982
- Nutritional composition of milk produced by mothers delivering pretermThe Journal of Pediatrics, 1980