Lack of detection of host associated differences in Newcastle disease viruses of genotype VIId isolated from chickens and geese
Open Access
- 13 September 2012
- journal article
- research article
- Published by Springer Science and Business Media LLC in Virology Journal
- Vol. 9 (1), 197
- https://doi.org/10.1186/1743-422x-9-197
Abstract
The goose is usually considered to be resistant even to strains of Newcastle disease virus (NDV) that are markedly virulent for chickens. However, ND outbreaks have been frequently reported in goose flocks in China since the late 1990s with the concurrent emergence of genotype VIId NDV in chickens. Although the NDVs isolated from both chickens and geese in the past 15 years have been predominantly VIId viruses, published data comparing goose- and chicken-originated ND viruses are scarce and controversial. In this paper, we compared genotype VIId NDVs originated from geese and chickens genetically and pathologically. Ten entire genomic sequences and 329 complete coding sequences of individual genes from genotype VIId NDVs of both goose- and chicken-origin were analyzed. We then randomly selected two goose-originated and two chicken-originated VIId NDVs and compared their pathobiology in both geese and chickens in vivo and in vitro with genotype IV virus Herts/33 as a reference. The results showed that all the VIId NDVs either from geese or from chickens shared high sequence homology and characteristic amino acid substitutions and clustered together in phylogenetic trees. In addition, geese and chickens infected by goose or chicken VIId viruses manifested very similar pathological features distinct from those of birds infected with Herts/33. There is no genetic or phenotypic difference between genotype VIId NDVs originated from geese and chickens. Therefore, no species-preference exists for either goose or chicken viruses and more attention should be paid to the trans-species transmission of VIId NDVs between geese and chickens for the control and eradication of ND.Keywords
This publication has 36 references indexed in Scilit:
- Entire genome sequence analysis of genotype IX Newcastle disease viruses reveals their early-genotype phylogenetic position and recent-genotype genome sizeVirology Journal, 2011
- Genetic diversity of Newcastle disease viruses isolated from domestic poultry species in Eastern China during 2005–2008Archiv für die gesamte Virusforschung, 2010
- Newcastle disease: Evolution of genotypes and the related diagnostic challengesInfection, Genetics and Evolution, 2010
- Genomic analysis of Newcastle disease virus strain NA-1 isolated from geese in ChinaArchiv für die gesamte Virusforschung, 2008
- Pathotypical Characterization and Molecular Epidemiology of Newcastle Disease Virus Isolates from Different Hosts in China from 1996 to 2005Journal of Clinical Microbiology, 2008
- Experimental Pathogenesis for Chickens, Turkeys, and Pigeons of Exotic Newcastle Disease Virus from an Outbreak in California during 2002-2003Veterinary Pathology, 2006
- Third genome size category of avian paramyxovirus serotype 1 (Newcastle disease virus) and evolutionary implicationsVirus Research, 2006
- Sequence variation in the Newcastle disease virus genomeVirus Research, 2006
- Genomic sequence of an isolate of Newcastle disease virus isolated from an outbreak in geese: a novel six nucleotide insertion in the non-coding region of the nucleoprotein geneArchiv für die gesamte Virusforschung, 2004
- Deduced amino acid sequences at the fusion protein cleavage site of Newcastle disease viruses showing variation in antigenicity and pathogenicityArchiv für die gesamte Virusforschung, 1993