Clinical Pharmacokinetics of Doxycycline and Minocycline
- 1 December 1988
- journal article
- review article
- Published by Springer Science and Business Media LLC in Clinical Pharmacokinetics
- Vol. 15 (6), 355-366
- https://doi.org/10.2165/00003088-198815060-00001
Abstract
Doxycycline and minocycline are second-generation tetracyclines. They are readily absorbed, distributed throughout the organism as a function of their lipophilicity and eliminated in both the urine and the faeces. The influence of age, renal disease, malnutrition and hyperlipidaemia is reviewed, together with the main pharmacokinetic interactions.Keywords
This publication has 59 references indexed in Scilit:
- Comparative pharmacokinetics of doxycycline and oxytetracycline in patients with hyperlipidemia.1985
- CorrespondenceJournal of Antimicrobial Chemotherapy, 1984
- Pharmacokinetics and plasma steady state levels of doxycycline in undernutrition.British Journal of Clinical Pharmacology, 1982
- Effect of Alcoholic Beverages on the Pharmacokinetics of Doxycycline in ManActa Pharmacologica et Toxicologica, 1982
- Pharmacokinetics of doxycycline polyphosphate after oral multiple dosing in humansEuropean Journal of Drug Metabolism and Pharmacokinetics, 1982
- Minocycline.1982
- [Use of doxycycline in human renal failure].1980
- Therapeutic implications of doxycycline and cephalothin concentrations in the female genital tract.1980
- The penetration of antibiotics into cerebrospinal fluid and brain tissueJournal of Antimicrobial Chemotherapy, 1978
- Clinical evaluation of intravenous minocycline.1977