Vasculitis Associated with All Trans Retinoic Acid (ATRA) in a Case with Acute Promyelocytic Leukemia
- 1 January 2003
- journal article
- case report
- Published by Taylor & Francis Ltd in Leukemia & Lymphoma
- Vol. 44 (3), 547-548
- https://doi.org/10.1080/1042819021000055101
Abstract
All trans retinoic acid is the drug of choice in the treatment of acute promyelocytic leukemia. But this drug has some side effects, some of which may be life-threatening. Retinoic acid syndrome is the most frequent and dangerous side effect of this differentiation inducing agent. Other side effects include Sweet's syndrome, vasculitis, hypercalcemia, bone marrow necrosis and fibrosis, thromboembolic events, erythema nodosum, granulomatous proliferation and some pulmonary complications. Here, we report vasculitis in a case with APL treated with ATRA and review the literature.This publication has 12 references indexed in Scilit:
- Sweet's syndrome associated with retinoic acid syndrome in a patient with promyelocytic leukemiaAnnals of Hematology, 2002
- Sweet`s syndrome during the treatment of acute promyelocytic leukemia with all - trans retinoic acidThe Korean Journal of Internal Medicine, 2001
- Diffuse Alveolar Hemorrhage with Underlying Pulmonary Capillaritis in the Retinoic Acid SyndromeAmerican Journal of Respiratory and Critical Care Medicine, 1998
- Sweet's Syndrome During Treatment with All-Trans Retinoic Acid in a Patient with Acute Promyelocytic LeukemiaLeukemia & Lymphoma, 1998
- Acute neutrophilic dermatosis with myeloblastic infiltrate in a leukemia patient receiving all-trans-retnoic acid therapyJournal of the American Academy of Dermatology, 1994
- All-trans Retinoic Acid for Acute Promyelocytic Leukemia: Results of the New York StudyAnnals of Internal Medicine, 1994
- Sweet's syndrome associated with trans-retinoic acid treatment in acute promyelocytic leukemiaClinical and Experimental Dermatology, 1994
- Acute Promyelocytic LeukemiaThe New England Journal of Medicine, 1993
- The "Retinoic Acid Syndrome" in Acute Promyelocytic LeukemiaAnnals of Internal Medicine, 1992
- Differentiation Therapy of Acute Promyelocytic Leukemia with Tretinoin (All-trans-Retinoic Acid)The New England Journal of Medicine, 1991