Hemodynamic variables and progression of acute kidney injury in critically ill patients with severe sepsis: data from the prospective observational FINNAKI study
Open Access
- 1 January 2013
- journal article
- research article
- Published by Springer Science and Business Media LLC in Critical Care
- Vol. 17 (6), R295
- https://doi.org/10.1186/cc13161
Abstract
Knowledge of the association of hemodynamics with progression of septic acute kidney injury (AKI) is limited. However, some recent data suggest that mean arterial pressure (MAP) exceeding current guidelines (60–65 mmHg) may be needed to prevent AKI. We hypothesized that higher MAP during the first 24 hours in the intensive care unit (ICU), would be associated with a lower risk of progression of AKI in patients with severe sepsis.Keywords
This publication has 38 references indexed in Scilit:
- Outcome of critically ill patients with acute kidney injury using the Acute Kidney Injury Network criteria*Critical Care Medicine, 2011
- Sepsis and Acute Kidney InjuryJournal of the American Society of Nephrology, 2011
- Histopathology of septic shock induced acute kidney injury: apoptosis and leukocytic infiltrationIntensive Care Medicine, 2009
- Incidence and outcomes of acute kidney injury in intensive care units: A Veterans Administration study*Critical Care Medicine, 2009
- Acute kidney injury in septic shock: clinical outcomes and impact of duration of hypotension prior to initiation of antimicrobial therapyIntensive Care Medicine, 2008
- Pathophysiology of septic acute kidney injury: What do we really know?Critical Care Medicine, 2008
- Early acute kidney injury and sepsis: a multicentre evaluationCritical Care, 2008
- Acute renal failure in patients with severe sepsis and septic shock--a significant independent risk factor for mortality: results from the German Prevalence StudyNephrology Dialysis Transplantation, 2007
- Acute Renal Failure in Critically Ill PatientsA Multinational, Multicenter StudyJAMA, 2005
- Acute Renal Failure and SepsisNew England Journal of Medicine, 2004