Facial implants have become increasingly more sophisticated in the past 10 to 15 years. The concept of “the ideal implant” has progressed from an inert material that interacts minimally with the host tissue to one that participates in the normal function of the tissues. A thorough understanding of their chemical properties is essential to understand the biologic events that occur around these materials after implantation. This article outlines the salient features of common materials encountered in facial implants used in plastic surgery.