INDUCTION OF T LYMPHOCYTES FROM PRECURSOR CELLS IN VITRO BY A PRODUCT OF THE THYMUS
Open Access
- 1 August 1973
- journal article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 138 (2), 479-482
- https://doi.org/10.1084/jem.138.2.479
Abstract
A product of mouse thymus induces cells found in the spleen and bone marrow of nu/nu mice (which lack a thymus), and in 14-day embryonic mouse liver, to differentiate in vitro into T lymphocytes (defined as cells bearing TL and Thy-1 antigens). Thus the in vitro T lymphocyte induction mechanism acts on a cell that is antecedent to any thymus-mediated process.This publication has 8 references indexed in Scilit:
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