Fabrication, Functionalization, and Application of Electrospun Biopolymer Nanofibers
- 25 August 2008
- journal article
- review article
- Published by Informa UK Limited in Critical Reviews in Food Science and Nutrition
- Vol. 48 (8), 775-797
- https://doi.org/10.1080/10408390802241325
Abstract
The use of novel nanostructured materials has attracted considerable interest in the food industry for their utilization as highly functional ingredients, high-performance packaging materials, processing aids, and food quality and safety sensors. Most previous application interest has focused on the development of nanoparticles. However, more recently, the ability to produce non-woven mats composed of nanofibers that can be used in food applications is beginning to be investigated. Electrospinning is a novel fabrication technique that can be used to produce fibers with diameters below 100 nm from (bio-) polymer solutions. These nanofibers have been shown to possess unique properties that distinguish them from non-woven fibers produced by other methods, e.g., melt-blowing. This is because first the process involved results in a high orientation of polymers within the fibers that leads to mechanically superior properties, e.g., increased tensile strengths. Second, during the spinning of the fibers from polymer solutions, the solvent is rapidly evaporated allowing the production of fibers composed of polymer blends that would typically phase separate if spun with other processes. Third, the small dimensions of the fibers lead to very high specific surface areas. Because of this the fiber properties may be greatly influenced by surface properties giving rise to fiber functionalities not found in fibers of larger sizes. For food applications, the fibers may find uses as ingredients if they are composed solely of edible polymers and GRAS ingredients, (e.g., fibers could contain functional ingredients such as nutraceuticals, antioxidants, antimicrobials, and flavors), as active packaging materials or as processing aids (e.g., catalytic reactors, membranes, filters ( Lala et al., 2007 Lala, N. L. , Ramaseshan, R. , Li, B. J. , Sundarrajan, S. , Barhate, R. S. , Liu, Y. J. and Ramakrishna, S. 2007. Fabrication of nanofibers with antimicrobial functionality used as filters: Protection against bacterial contaminants. Biotechnology and Bioengineering., 97(6): 1357 [Google Scholar] ), and sensors ( Manesh et al., 2007 Manesh, K. M. , Santhosh, P. , Gopalan, A. and Lee, K. P. 2007. Electrospun poly(vinylidene fluoride)/poly(aminophenylboronic acid) composite nanofibrous membrane as a novel glucose sensor. Analytical Biochemistry., 360(2): 189 [Google Scholar] ; Ren et al., 2006 Ren, G. L. , Xu, X. H. , Liu, Q. , Cheng, J. , Yuan, X. Y. , Wu, L. L. and Wan, Y. Z. 2006. Electrospun poly(vinyl alcohol)/glucose oxidase biocomposite membranes for biosensor applications. Reactive & Functional Polymers., 66(12): 1559 [Google Scholar] ; Sawicka et al., 2005 Sawicka, K. , Gouma, P. and Simon, S. 2005. Electrospun biocomposite nanofibers for urea biosensing. Sensors and Actuators B-Chemical., 108(1–2): 585 [Google Scholar] ). This review is therefore intended to introduce interested food and agricultural scientists to the concept of nano-fiber manufacturing with a particular emphasis on the use of biopolymers. We will review typical fabrication set-ups, discuss the influence of process conditions on nanofiber properties, and then review previous studies that describe the production of biopolymer-based nanofibers. Finally we briefly discuss emerging methods to further functionalize fibers and discuss potential applications in the area of food science and technology.Keywords
This publication has 136 references indexed in Scilit:
- Preparation of polyurethane cationomer nanofiber mats for use in antimicrobial nanofilter applicationsMaterials Letters, 2007
- Hybrid nanofibrous membranes of PLGA/chitosan fabricated via an electrospinning arrayJournal of Biomedical Materials Research Part A, 2007
- Electrospun cellulose acetate fibers: effect of solvent system on morphology and fiber diameterCellulose, 2007
- Electrospinning of collagen–chitosan complexMaterials Letters, 2006
- Curcumin: The story so farEuropean Journal Of Cancer, 2005
- Characterization of gelatin nanofiber prepared from gelatin–formic acid solutionPolymer, 2005
- Electrospinning of linear homopolymers of poly(methyl methacrylate): exploring relationships between fiber formation, viscosity, molecular weight and concentration in a good solventPolymer, 2005
- Chitin and chitosan nanofibers: electrospinning of chitin and deacetylation of chitin nanofibersPolymer, 2004
- Mimetics of Eggshell Membrane Protein Fibers by ElectrospinningMacromolecular Rapid Communications, 2004
- Electrospinning process and applications of electrospun fibersJournal of Electrostatics, 1995