MRI and localized proton spectroscopy in human leg muscle at 7 tesla using longitudinal traveling waves
- 23 January 2010
- journal article
- research article
- Published by Wiley in Magnetic Resonance in Medicine
- Vol. 63 (2), 297-302
- https://doi.org/10.1002/mrm.22262
Abstract
Using a small resonant loop to produce a longitudinal traveling wave on a human 7-T system allows MR to be performed over the entire volume of the human leg. We have used this capability to perform localized proton MR spectroscopy of the lipid composition of muscle in volunteers with a coil placed approximately 30 cm away from the region of interest. Spectra with a reasonable signal-to-noise ratio can be acquired in a clinically relevant data acquisition time of less than 5 min using the loop in transmit/receive mode, maintaining the full flexibility to acquire spectra from any part of the calf and/or thigh. If a local receive coil is used in combination with the remote transmit coil, then the signal-to-noise improves significantly, as expected.Keywords
Funding Information
- National Institutes of Health (R01 EB000454)
This publication has 23 references indexed in Scilit:
- GRAPPA-based susceptibility-weighted imaging of normal volunteers and patients with brain tumor at 7 TMagnetic Resonance Imaging, 2009
- Quantitative in vivo magnetic resonance imaging of multiple sclerosis at 7 Tesla with sensitivity to ironAnnals of Neurology, 2008
- Orientation of lipid strands in the extracellular compartment of muscle: Effect on quantitation of intramyocellular lipidsMagnetic Resonance in Medicine, 2008
- Imaging and analysis of lenticulostriate arteries using 7.0‐Tesla magnetic resonance angiographyMagnetic Resonance in Medicine, 2008
- In vivo measurement of glycine with short echo-time 1H MRS in human brain at 7 TMagnetic Resonance Materials in Physics, Biology and Medicine, 2008
- Composition of adipose tissue and marrow fat in humans by 1H NMR at 7 TeslaJournal of Lipid Research, 2008
- High-field MRI of brain cortical substructure based on signal phaseProceedings of the National Academy of Sciences of the United States of America, 2007
- Robust detection of ocular dominance columns in humans using Hahn Spin Echo BOLD functional MRI at 7 TeslaNeuroImage, 2007
- Sensitivity of single-voxel 1H-MRS in investigating the metabolism of the activated human visual cortex at 7 TMagnetic Resonance Imaging, 2006
- In vivo 1H NMR spectroscopy of the human brain at 7 TMagnetic Resonance in Medicine, 2001