Helicobacter pylorihas no influence on distal gastric cancer survival
Open Access
- 1 June 2011
- journal article
- Published by FapUNIFESP (SciELO) in Arquivos de Gastroenterologia
- Vol. 48 (2), 109-111
- https://doi.org/10.1590/s0004-28032011000200005
Abstract
CONTEXT: There is some evidence that Helicobacter pylori correlates with distal gastric cancer genesis. However, few studies analyzed the survival related to H. pylori infection. OBJECTIVE: To correlate gastric cancer survival and H. pylori infection. METHODS: Sixty-eight patients with distal gastric cancer that underwent subtotal gastrectomy were studied. Minimal follow-up was 1 month. H. pylori infection was confirmed by biopsy. RESULTS: Thirty-four patients (19 males (55.9%), mean age 60.9 ± 14.03, range 33-82 years) were H. pylori positive. Thirty-four patients (16 males (47.1%), mean age 57.9 ± 13.97, range 27-85 years) were H. pylori negative. Groups were comparable in regards to age (P = 0.4), gender (P = 0.5), stage [T (P = 0.2), N (P = 0.6) and M (P = 0.9)]. Survival was not different when groups were compared [P = 0.1616 (hazard ratio 0.6834, 95% CI 0.4009 to 1.1647)]. CONCLUSIONS: H. pylori infection does not affect distal gastric cancer survival.Keywords
This publication has 9 references indexed in Scilit:
- Elevated Serum Matrix Metalloproteinase-3 and -7 in H. pylori-Related Gastric Cancer Can Be Biomarkers Correlating with a Poor SurvivalDigestive Diseases and Sciences, 2009
- Negative Helicobacter pylori status is associated with poor prognosis in patients with gastric cancerCancer, 2009
- Gastric cancerCritical Reviews in Oncology/Hematology, 2009
- Helicobacter pylori as a prognostic indicator after curative resection of gastric carcinoma: a prospective studyThe Lancet Oncology, 2006
- Prevalence of Helicobacter pyloriinfection and associated factors among adults in Southern Brazil: a population-based cross-sectional studyBMC Public Health, 2005
- The relation of Helicobacter pylori to gastric adenocarcinoma and lymphoma: pathophysiology, epidemiology, screening, clinical presentation, treatment, and preventionMedical Clinics of North America, 2005
- Gastric AdenocarcinomaAnnals of Surgery, 2005
- Better Survival ofHelicobacter pyloriInfected Patients with Early Gastric Cancer Is Related to a Higher Level of Thomsen‐Friedenreich Antigen‐Specific AntibodiesImmunological Investigations, 2003
- Comparison between resectable gastric adenocarcinomas seropositive and seronegative for Helicobacter pyloriBritish Journal of Surgery, 1995