Lack of association between intrachromosomal gene conversion and reciprocal exchange
- 31 July 1984
- journal article
- research article
- Published by Springer Science and Business Media LLC in Nature
- Vol. 310 (5980), 748-753
- https://doi.org/10.1038/310748a0
Abstract
The association of reciprocal exchange with intrachromosomal gene conversion was examined using an inverted repeat at the HIS3 locus of Saccharomyces cerevisiae. Intrachromosomal gene conversions between the duplicated inverted sequences are frequent. In contrast to gene conversion events between homologous chomosomes, intrachromosomal gene conversion is not associated with reciprocal exchange in flanking sequences. This observation has important consequences for the role of gene conversion in the maintenance of multigene families.This publication has 43 references indexed in Scilit:
- Molecular drive: a cohesive mode of species evolutionNature, 1982
- The extent to which gene conversion can change allele frequencies in populationsGenetics Research, 1982
- Gene conversion between duplicated genetic elements in yeastNature, 1981
- Heavy chain variable region contribution to the NPb family of antibodies: somatic mutation evident in a γ2a variable regionCell, 1981
- Gene conversion: Some implications for immunoglobulin genesCell, 1981
- Homology and concerted evolution at the α1 and α2 loci of human α-globinNature, 1981
- Intrachromosomal gene conversion in yeastNature, 1981
- Human fetal gγ- and Aγ-globin genes: Complete nucleotide sequences suggest that DNA can be exchanged between these duplicated genesCell, 1980
- Meiotic Gene Conversion: A Signal of the Basic Recombination Event in YeastCold Spring Harbor Symposia on Quantitative Biology, 1979
- Conversion-Associated Recombination in YeastProceedings of the National Academy of Sciences of the United States of America, 1972