Degeneracy of the genetic code and stability of the base pair at the second position of the anticodon
- 21 May 2008
- journal article
- Published by Cold Spring Harbor Laboratory in RNA
- Vol. 14 (7), 1264-1269
- https://doi.org/10.1261/rna.1029808
Abstract
With an analysis of the structural constraints of the anticodon–codon interaction within the decoding center of the ribosome, we show that the extent of degeneracy at the third position of the anticodon is determined by the level of stability of the base pair at the second position.Keywords
This publication has 33 references indexed in Scilit:
- The wobble hypothesis revisited: Uridine-5-oxyacetic acid is critical for reading of G-ending codonsRNA, 2007
- tRNA’s Wobble Decoding of the Genome: 40 Years of ModificationJournal of Molecular Biology, 2007
- KISS: The kinetoplastid RNA editing sequence search toolRNA, 2006
- Idiosyncratic tuning of tRNAs to achieve uniform ribosome bindingNature Structural & Molecular Biology, 2005
- CH···O Hydrogen Bonds at Protein-Protein InterfacesJournal of Biological Chemistry, 2002
- Physico-chemical Constraints Connected with the Coding Properties of the Genetic SystemJournal of Theoretical Biology, 2000
- Singly and Bifurcated Hydrogen-bonded Base-pairs in tRNA Anticodon Hairpins and RibozymesJournal of Molecular Biology, 1999
- Expanded sequence dependence of thermodynamic parameters improves prediction of RNA secondary structureJournal of Molecular Biology, 1999
- Translation of Synonymous Codons in Family Boxes byMycoplasma capricolumtRNAs with Unmodified Uridine or Adenosine at the First Anticodon PositionJournal of Molecular Biology, 1995
- Problem and paradigms: Unconventional methods in codon readingBioEssays, 1986