Age-Related Differences in the Human Vitreoretinal Interface
- 1 July 1991
- journal article
- research article
- Published by American Medical Association (AMA) in American Journal of Ophthalmology
- Vol. 109 (7), 966-971
- https://doi.org/10.1001/archopht.1991.01080070078039
Abstract
• Age-related differences in vitreoretinal adhesion were investigated in 59 human eyes from donors aged from 33 weeks of gestation to 94 years with the use of dark-field and electron microscopy of whole vitreous. In all eyes from individuals aged 21 years or older, dissection of the retina off the vitreous resulted in cleavage between the vitreous cortex and the internal limiting lamina. However, in six (40%) of 15 eyes from individuals aged 20 years or younger, the internal limiting lamina remained adherent to the vitreous cortex in an area that encompassed the macula, temporal arcades, and peripapillary posterior pole. Ultrastructural studies revealed inner portions of Müller's cells that were attached to the posterior aspect of the internal limiting lamina. These results suggested that, in youth, there is adhesion between the vitreous cortex and internal limiting lamina that is stronger than Müller's cell itself and is topographically more extensive than previously thought.Keywords
This publication has 13 references indexed in Scilit:
- Chapter-254 Functional Anatomy of the VitreousPublished by Jaypee Brothers Medical Publishing ,2002
- Age-related changes in human vitreous structureAlbrecht von Graefes Archiv für Ophthalmologie, 1987
- Macular Hemorrhages Associated With Posterior Vitreous DetachmentAmerican Journal of Ophthalmology, 1986
- Role of the vitreous in cystoid macular edemaSurvey of Ophthalmology, 1984
- Pathogenesis of cystoid macular edema: An anatomic consideration of vitreoretinal adhesionsSurvey of Ophthalmology, 1984
- Biomicroscopic Study of the Vitreous in Macular BreaksOphthalmology, 1983
- Prognostic Value of Vitreous Findings in Diabetic RetinopathyAmerican Journal of Ophthalmology, 1982
- Vitreous Changes in Retinal Branch Vein OcclusionOphthalmology, 1981
- The Structure of the Vitreous Body and the Suspensory Ligaments of the LensAmerican Journal of Ophthalmology, 1961
- Zur Genese der hinteren GlaskörperabhebungOphthalmologica, 1956