Photocatalytic [2 + 2] Cycloadditions of Enones with Cleavable Redox Auxiliaries
- 9 February 2012
- journal article
- letter
- Published by American Chemical Society (ACS) in Organic Letters
- Vol. 14 (4), 1110-1113
- https://doi.org/10.1021/ol3000298
Abstract
α,β-Unsaturated 2-imidazolyl ketones undergo [2 + 2] cycloaddition with a variety of Michael acceptors upon irradiation with visible light in the presence of Ru(bpy)32+. Cleavage of the imidazolyl auxiliary from the cycloadducts affords cyclobutane carboxamides, esters, thioesters, and acids that would not be accessible from direct cycloaddition of the corresponding unsaturated carbonyl compounds.Keywords
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