Genetic Landscape of Somatic Mutations in a Large Cohort of Sporadic Medullary Thyroid Carcinomas Studied by Next-Generation Targeted Sequencing
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Open Access
- 1 October 2019
- journal article
- research article
- Published by Elsevier BV in iScience
- Vol. 20, 324-336
- https://doi.org/10.1016/j.isci.2019.09.030
Abstract
No abstract availableKeywords
Funding Information
- Associazione Italiana per la Ricerca sul Cancro
- Agenzia Italiana del Farmaco (AIFA-2016-02365049)
- Progetto di Ricerca di Ateneo (PRA_2018_27)
- University of Pisa
This publication has 43 references indexed in Scilit:
- SomaticRASMutations Occur in a Large Proportion of SporadicRET-Negative Medullary Thyroid Carcinomas and Extend to a Previously Unidentified ExonJournal of Clinical Endocrinology & Metabolism, 2012
- Low Prevalence of the Somatic M918T RET Mutation in Micro-Medullary Thyroid CancerThyroid®, 2012
- Activating mutation in MET oncogene in familial colorectal cancerBMC Cancer, 2011
- RET genetic screening of sporadic medullary thyroid cancer (MTC) allows the preclinical diagnosis of unsuspected gene carriers and the identification of a relevant percentage of hidden familial MTC (FMTC)Clinical Endocrinology, 2011
- Vandetanib for the Treatment of Patients With Locally Advanced or Metastatic Hereditary Medullary Thyroid CancerJournal of Clinical Oncology, 2010
- Molecular genetics of medullary thyroid carcinoma: the quest for novel therapeutic targetsJournal of Molecular Endocrinology, 2009
- Mechanisms of Disease: cancer targeting and the impact of oncogenic RET for medullary thyroid carcinoma therapyNature Clinical Practice Oncology, 2006
- RETProto-Oncogene: A Review and Update of Genotype–Phenotype Correlations in Hereditary Medullary Thyroid Cancer and Associated Endocrine TumorsThyroid®, 2005
- Overexpression of endoplasmic reticulum molecular chaperone GRP94 and GRP78 in human lung cancer tissues and its significanceCancer Detection Prevention, 2005
- Loss of the exon encoding the juxtamembrane domain is essential for the oncogenic activation of TPR-METOncogene, 1999