A comparative study: conventional preparation and ThinPrep® 2000 in respiratory cytology
- 1 December 2001
- journal article
- research article
- Published by Wiley in Cytopathology
- Vol. 12 (6), 390-398
- https://doi.org/10.1046/j.1365-2303.2001.00351.x
Abstract
A comparative study: conventional preparation and ThinPrep 2000 in respiratory cytology In order to compare and contrast conventional preparation (CP) with ThinPrep® 2000 (TP) in respiratory cytology, 207 samples were divided equally and processed by the two different preparation methods, generating three CP and one TP slide per sample. No lesion identified by CP was missed by TP and there were no significant differences between TP and CP in the diagnostic categories. However, two cases of squamous cell carcinoma were detected on TP which had been classified as unsatisfactory and moderate squamous dyskaryosis, respectively, on CP. ThinPrep was found to be superior to CP in many respects as it provided standardized preparations in a greater proportion of cases and problems such as cell overlapping and background debris were markedly reduced. In several instances the diagnostic accuracy in CP was compromised by smears that were either too thick, too thin, or too scanty. Cell preservation was also better on TP when compared with CP, facilitating more accurate diagnosis and significantly reducing the primary screening and reporting time, especially of sputum samples. A major advantage of TP methodology is the fact that it facilitates optimal use of skilled cytotechnologists and streamlines the workflow in the laboratory.Keywords
This publication has 9 references indexed in Scilit:
- Thin-layer technology: Tempered enthusiasmDiagnostic Cytopathology, 2000
- Interpretation of fine‐needle aspirates processed by the Thin Prep® technique: Cytologic artifacts and diagnostic pitfalls. *Diagnostic Cytopathology, 2000
- Exfoliative cytology of primary poorly differentiated (small‐cell) neuroendocrine carcinoma of the uterine cervix in ThinPrep® material: A case reportDiagnostic Cytopathology, 2000
- Interpretation of fine‐needle aspirates processed by the Thin Prep® technique: Cytologic artifacts and diagnostic pitfalls.Diagnostic Cytopathology, 2000
- Recent advances in thin-layer cytology.Diagnostic Cytopathology, 1998
- Comparison of ThinPrep and conventional preparations: Nongynecologic cytology evaluationDiagnostic Cytopathology, 1997
- Comparison of ThinPrep and conventional preparations: Nongynecologic cytology evaluationDiagnostic Cytopathology, 1997
- Nongynecologic Cytology Utilizing the ThinPrep ProcessorActa Cytologica, 1996
- Comparison of conventional and thinprep preparations of mucoid cytology samplesDiagnostic Cytopathology, 1995