Randomized, Double-Blind Six-Month Trial of Prednisone in Duchenne's Muscular Dystrophy
- 15 June 1989
- journal article
- clinical trial
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 320 (24), 1592-1597
- https://doi.org/10.1056/nejm198906153202405
Abstract
We performed a randomized, double-blind, controlled six-month trial of prednisone in 103 boys with Duchenne's muscular dystrophy (age, 5 to 15 years). The patients were assigned to one of three regimens: prednisone, 0.75 mg per kilogram of body weight per day (n = 33); prednisone, 1.5 mg per kilogram per day (n = 34); or placebo (n = 36). The groups were initially comparable in all measures of muscle function.Keywords
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