Principles of CDK regulation
- 9 March 1995
- journal article
- review article
- Published by Springer Science and Business Media LLC in Nature
- Vol. 374 (6518), 131-134
- https://doi.org/10.1038/374131a0
Abstract
As key regulators of the cell cycle, the cyclin-dependent kinases must be tightly regulated by extra- and intracellular signals. The activity of cyclin-dependent kinases is controlled by four highly conserved biochemical mechanisms, forming a web of regulatory pathways unmatched in its elegance and intricacy.Keywords
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