Iron and Malaria Interactions: Programmatic Ways Forward
Open Access
- 1 July 2012
- journal article
- Published by Elsevier BV in Advances in Nutrition: An International Review Journal
- Vol. 3 (4), 579-582
- https://doi.org/10.3945/an.111.000885
Abstract
Around one-quarter of the world’s children suffer from iron deficiency anemia, and many of them live in malaria-endemic areas. However, there is evidence that iron supplements can increase risk of severe malaria morbidity. The dilemma is how to move forward with interventions to prevent iron deficiency and its consequences in young children, using strategies that minimize risks of malaria and related infections. Screening for iron deficiency is problematic for several reasons. Two complementary strategies are suggested for moving forward with interventions to prevent iron deficiency in children exposed to malaria. The first is to reduce exposure to iron in the form of supplements by: adopting a lifecycle approach to pediatric iron deficiency beginning in utero, using the lowest adequate dose, and giving iron in or with foods. The second is to coordinate iron interventions with malaria control efforts. To stop all iron interventions in malaria-endemic areas is an unreasonable policy option. While research findings continue to increase our understanding, there are also programmatic ways forward with the knowledge at hand.Keywords
This publication has 17 references indexed in Scilit:
- Targeted Provision of Oral Iron: The Evolution of a Practical Screening OptionAdvances in Nutrition: An International Review Journal, 2012
- Fortification Iron as Ferrous Sulfate Plus Ascorbic Acid Is More Rapidly Absorbed Than as Sodium Iron EDTA but Neither Increases Serum Nontransferrin-Bound Iron in Women1–3Journal of Nutrition, 2011
- A Micronutrient Powder with Low Doses of Highly Absorbable Iron and Zinc Reduces Iron and Zinc Deficiency and Improves Weight-For-Age Z-Scores in South African ChildrenJournal of Nutrition, 2011
- Impact of Artemisinin-Based Combination Therapy and Insecticide-Treated Nets on Malaria Burden in ZanzibarPLoS Medicine, 2007
- Effect of expanded insecticide-treated bednet coverage on child survival in rural Kenya: a longitudinal studyThe Lancet, 2007
- Child development: risk factors for adverse outcomes in developing countriesThe Lancet, 2007
- Effect of timing of umbilical cord clamping on iron status in Mexican infants: a randomised controlled trialThe Lancet, 2006
- Effect of routine prophylactic supplementation with iron and folic acid on preschool child mortality in southern Nepal: community-based, cluster-randomised, placebo-controlled trialThe Lancet, 2006
- Effects of routine prophylactic supplementation with iron and folic acid on admission to hospital and mortality in preschool children in a high malaria transmission setting: community-based, randomised, placebo-controlled trialThe Lancet, 2006
- Proposed Nutrient Composition for Fortified Complementary FoodsJournal of Nutrition, 2003