Increase in fibronectin in the deep dermis of involved skin in progressive systemic sclerosis
Open Access
- 1 September 1979
- journal article
- research article
- Published by Wiley in Arthritis & Rheumatism
- Vol. 22 (9), 983-987
- https://doi.org/10.1002/art.1780220906
Abstract
The distribution and amount of fibronectin in both involved and uninvolved skin from scleroderma patients and controls were compared by indirect immunofluorescence. A marked increase in fibronectin was found in the deep dermis of involved scleroderma skin, while the subepidermal papillary regions of all specimens revealed little variation in fibronectin content. The distribution of the accumulated fibronectin appeared to parallel that of the accumulated collagen in the involved reticular dermis.This publication has 20 references indexed in Scilit:
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