Patient Specific Dosimetry Phantoms Using Multichannel LDDMM of the Whole Body
Open Access
- 1 January 2011
- journal article
- research article
- Published by Hindawi Limited in International Journal of Biomedical Imaging
- Vol. 2011, 1-9
- https://doi.org/10.1155/2011/481064
Abstract
This paper describes an automated procedure for creating detailed patient-specific pediatric dosimetry phantoms from a small set of segmented organs in a child's CT scan. The algorithm involves full body mappings from adult template to pediatric images using multichannel large deformation diffeomorphic metric mapping (MC-LDDMM). The parallel implementation and performance of MC-LDDMM for this application is studied here for a sample of 4 pediatric patients, and from 1 to 24 processors. 93.84% of computation time is parallelized, and the efficiency of parallelization remains high until more than 8 processors are used. The performance of the algorithm was validated on a set of 24 male and 18 female pediatric patients. It was found to be accurate typically to within 1-2 voxels (2–4 mm) and robust across this large and variable data set.Keywords
Funding Information
- National Institutes of Health (1S10RR025053-01, R01-EB001838, P41-RR015241)
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