Comorbidities of dry eye disease: a nationwide population‐based study
Open Access
- 31 August 2010
- journal article
- Published by Wiley in Acta Ophthalmologica
- Vol. 90 (7), 663-668
- https://doi.org/10.1111/j.1755-3768.2010.01993.x
Abstract
Purpose: To investigate the comorbidities of dry eye disease in a nationwide population-based data in Taiwan. Methods: This study features a study group and a comparison group. The study group comprised 12 007 patients who sought ambulatory care for treatment of dry eye in 2005 and 2006. In total, 36 021 randomly selected patients were in the comparison group. Conditional logistic regression analyses conditioned on gender, age, monthly income and level of urbanization of the community in which the patient resided were conducted to calculate the odds ratio (OR) for each of 33 comorbidities among patients with and without dry eye disease. Results: The regression analyses revealed that compared to patients without dry eye disease, patients with dry eye disease were more likely to have comorbidities of ischaemic heart disease (OR = 1.36), hyperlipidaemia (OR = 1.68), cardiac arrhythmias (OR = 1.55), peripheral vascular disorders (OR = 1.57), stroke (OR = 1.31), migraines (OR = 1.76), myasthenia gravis (OR = 2.85), RA (OR = 2.86), systemic lupus erythematosus (OR = 3.98), asthma (OR = 1.25), pulmonary circulation disorders (OR = 1.37), diabetes with complications (OR = 1.31), hypothyroidism (OR = 1.94), liver diseases (OR = 1.71), peptic ulcers (OR = 1.76), hepatitis B (OR = 1.64), deficiency anaemias (OR = 1.31), depression (OR = 2.11), psychoses (OR = 1.87) and solid tumours without metastasis (OR = 1.41). Conclusions: This study demonstrates significantly higher prevalence of medical comorbidities in patients with dry eye disease in Taiwan.Keywords
This publication has 27 references indexed in Scilit:
- Hepatitis B virus infectionThe Lancet, 2009
- Long-term Incidence of Dry Eye in an Older PopulationOptometry and Vision Science, 2008
- Tear Film Function in Type 2 Diabetic Patients with RetinopathyOphthalmologica, 2008
- Association between Symptoms and Signs of Dry Eye among an Elderly Chinese Population in Taiwan: The Shihpai Eye StudyPublished by Association for Research in Vision and Ophthalmology (ARVO) ,2005
- Clinical mini-review: systemic lupus erythematosus and the eyeOcular Immunology and Inflammation, 2004
- Prevalence of dry eye among an elderly Chinese population in TaiwanOphthalmology, 2003
- The Diagnosis and Management of Dry EyeCornea, 2000
- The Pathology of Dry EyeCornea, 1998
- The epidemiology of dry eye in Melbourne, Australia, Historical imageOphthalmology, 1998
- Dry Eye SyndromesInternational Ophthalmology Clinics, 1970