Corneal Backscatter Analysis by In Vivo Confocal Microscopy: Fellow Eye Comparison of Small Incision Lenticule Extraction and Femtosecond Laser-Assisted LASIK
Open Access
- 5 March 2014
- journal article
- research article
- Published by Hindawi Limited in Journal of Ophthalmology
- Vol. 2014 (3), 1-8
- https://doi.org/10.1155/2014/265012
Abstract
Purpose. To evaluate and compare corneal backscatter from anterior stroma between small incision lenticule extraction (SMILE) and femtosecond laser-assisted LASIK (femto-LASIK).Methods. A cohort of 60 eyes of 30 patients was randomized to receive SMILE in one eye and femto-LASIK in the fellow eye. In vivo confocal microscopy was performed at 1 week and 1, 3, and 6 months after surgery. The main outcome measurements were maximum backscattered intensity and the depth from which it was measured, the backscattered light intensity 30 μm below Bowman’s membrane at the flap interface and 150 μm below the superficial epithelium, and the number of refractive particles at the flap interface.Results. The mean backscattered light intensity (LI) at all measured depths and the maximum backscattered LI were higher in the SMILE group than the femto-LASIK group at all postoperative visits. LI differences at 1 week and 1- and 3-month visits were statistically significant (,05). LI differences at 6 months were not statistically significant. There was no difference in the number of refractive particles at the flap interface between the groups at any visit.Conclusions. SMILE results in increased backscattered LI in the anterior stroma when compared with femto-LASIK were evaluated.
This publication has 21 references indexed in Scilit:
- Femtosecond (FS) laser vision correction procedure for moderate to high myopia: a prospective study of ReLEx® flex and comparison with a retrospective study of FS‐laser in situ keratomileusisActa Ophthalmologica, 2012
- Early Corneal Wound Healing and Inflammatory Responses after Refractive Lenticule Extraction (ReLEx)Investigative Ophthalmology & Visual Science, 2011
- Wide-Range Calibration of Corneal Backscatter Analysis by In Vivo Confocal MicroscopyInvestigative Ophthalmology & Visual Science, 2011
- Surface Quality of Porcine Corneal Lenticules after Femtosecond Lenticule ExtractionOphthalmic Research, 2011
- Results of small incision lenticule extraction: All-in-one femtosecond laser refractive surgeryJournal of Cataract & Refractive Surgery, 2011
- Laser in situ keratomileusis flap complications using mechanical microkeratome versus femtosecond laser: Retrospective comparisonJournal of Cataract & Refractive Surgery, 2010
- Small incision corneal refractive surgery using the small incision lenticule extraction (SMILE) procedure for the correction of myopia and myopic astigmatism: results of a 6 month prospective studyBritish Journal of Ophthalmology, 2010
- Endothelial Involvement in Herpes Simplex Virus Keratitis: An In Vivo Confocal Microscopy StudyOphthalmology, 2009
- Quantitative assessment of corneal wound healing following IntraLASIK using in vivo confocal microscopy.2008
- Incidence of diffuse lamellar keratitis after laser in situ keratomileusis associated with the IntraLase 15 kHz femtosecond laser and Moria M2 microkeratomeJournal of Cataract & Refractive Surgery, 2008