VITREOUS SURGERY WITH AND WITHOUT INTERNAL LIMITING MEMBRANE PEELING FOR MACULAR HOLE REPAIR
- 1 October 2004
- journal article
- clinical trial
- Published by Ovid Technologies (Wolters Kluwer Health) in Retina
- Vol. 24 (5), 721-727
- https://doi.org/10.1097/00006982-200410000-00006
Abstract
To compare surgical results for idiopathic macular holes with and without internal limiting membrane (ILM) peeling in a series of consecutive patients during an 8-year period. A retrospective, nonrandomized, comparative trial. Four hundred seventeen eyes with macular holes without ILM peeling were compared with 175 eyes with ILM peeling. All eyes underwent pars plana vitrectomy with intravitreous gas, followed by head-down positioning. No adjunctive therapies were used. Comparison of closure and reopening rates and visual acuity with and without ILM peeling was analyzed. Initial success rate significantly improved from 81% to 92% with ILM peeling. ILM peeling significantly improved the initial success rates in all categories of preoperative features. Reopening rates significantly decreased from 7% to 0.6% with ILM peeling. Among successful cases, line improvement was 6.0 in ILM-reserved eyes and 5.8 in ILM-peeled eyes. Among all cases, line improvement was 5.4 in ILM-reserved eyes and 5.7 in ILM-peeled eyes. Initial success rate of holes measuring more than 400 μm was significantly less than that of holes measuring less than 400 μm with or without ILM peeling. Initial success rate of holes older than 6 months old was significantly less than that for holes less than 6 months old without ILM peeling. Internal limiting membrane peeling shows high closure and low reopening rates in macular hole surgery. ILM peeling is beneficial in older holes but is limited in larger holes. ILM peeling does not significantly improve visual acuity.Keywords
This publication has 25 references indexed in Scilit:
- Long-term follow-up after macular hole surgery with internal limiting membrane peelingAmerican Journal of Ophthalmology, 2002
- Internal limiting membrane peeling in macular hole surgeryOphthalmology, 2001
- Indocyanine green–assisted peeling of the retinal internal limiting membrane13The authors have no financial interest in products mentioned in this article.Ophthalmology, 2000
- Macular hole surgery with and without internal limiting membrane peelingOphthalmology, 2000
- Staining of Internal Limiting Membrane in Macular Hole SurgeryAmerican Journal of Ophthalmology, 2000
- Internal limiting membrane removal in the management of full-thickness macular holesAmerican Journal of Ophthalmology, 2000
- Macular hole surgery in 2000Current Opinion in Opthalmology, 2000
- Macular hole surgery with internal-limiting membrane peeling and intravitreous airOphthalmology, 1999
- MACULAR HOLE SURGERY USING THROMBIN-ACTIVATED FIBRINOGEN AND SELECTIVE REMOVAL OF THE INTERNAL LIMITING MEMBRANERetina, 1998
- Ultrastructural Features of Tissue Removed During Idiopathic Macular Hole SurgeryAmerican Journal of Ophthalmology, 1996