Anaplastic spindle-cell and giant-cell tumors of the thyroid gland
Open Access
- 1 July 1972
- Vol. 30 (1), 113-127
- https://doi.org/10.1002/1097-0142(197207)30:1<113::aid-cncr2820300118>3.0.co;2-e
Abstract
Fifty‐three cases of anaplastic spindle‐cell and giant‐cell tumors of the thyroid gland were found in the files of the University of Michigan Medical Center in a 37‐year period (1932‐1969). Of these, 42 were found with other well‐differentiated thyroid carcinomas: papillary, follicular, Hürthle cell, clear cell, and medullary carcinomas. Data from this report and the recent literature support the conclusion that anaplastic tumors of the thyroid gland probably arise in preexisting well‐differentiated thyroid carcinomas. The grim prognosis for anaplastic carcinomas of the thyroid gland is reemphasized in this study; 49 of the 53 patients died within the first year after a histologic diagnosis was established.Keywords
This publication has 9 references indexed in Scilit:
- Anaplastic thyroid cancer twelve years after radioiodine therapyCancer, 1969
- Thyroid carcinoma—Biologic behavior and mortality:Postmortem findings in 42 cases, including 27 in which the disease was fatalCancer, 1966
- Spindle and giant cell metaplasia in papillary carcinoma of the thyroidThe American Journal of Surgery, 1965
- Carcinosarcoma of the Thyroid Gland: Report of Two CasesSouthern Medical Journal, 1964
- Thyroid carcinoma.Classification, intraglandular dissemination, and clinicopathological study based upon whole organ sections of 80 glandsCancer, 1963
- Papillary cancer of the thyroid. A review of 25 years of experienceCancer, 1958
- Fibrosarcoma involving the thyroid gland of a sheep given I131 dailyCancer, 1957
- OF THE ORIGIN, CHARACTERISTICS AND BEHAVIOR OF THYROID CANCER*Journal of Clinical Endocrinology & Metabolism, 1954