Serum Anticonvulsant Concentrations in Epileptic Patients with Mental Symptoms
- 1 May 1974
- journal article
- Published by Royal College of Psychiatrists in The British Journal of Psychiatry
- Vol. 124 (582), 440-445
- https://doi.org/10.1192/bjp.124.5.440
Abstract
The introduction of techniques for the measurement of the serum concentrations of anticonvulsant drugs has opened up new opportunities of studying epilepsy in many of its aspects. Until the present time authors have studied variations in, and factors effecting, the metabolism of the drugs, and the relationship of serum drug concentrations to seizure control and well known side effects (see Woodbury, Penry and Schmidt, 1972). In this paper we report some preliminary observations on drug concentrations in patients with and without marked changes in their mental state.Keywords
This publication has 11 references indexed in Scilit:
- Relationships between serum and cerebrospinal fluid anticonvulsant drug and folic acid concentrations in epileptic patientsNeurology, 1972
- Variation in Response to Anticonvulsants in a Group of Epileptic PatientsArchives of Neurology, 1972
- Acute effects of diphenylhydantoin in relation to plasma levels: Behavioural and psychophysiological studiesPsychological Medicine, 1972
- The distribution of plasma phenytoin levels in epileptic patientsJournal of Neurology, Neurosurgery & Psychiatry, 1970
- Pseudodegenerative Disease Due to Diphenylhydantoin IntoxicationArchives of Neurology, 1969
- The neurologic hazards ofdiphenylhydantoin in childhoodThe Journal of Pediatrics, 1968
- Diphenylhydantoin Metabolism, Blood Levels, and ToxicityArchives of Neurology, 1964
- The Schizophrenia-like Psychoses of EpilepsyThe British Journal of Psychiatry, 1963
- Personality in epilepsy.Published by American Psychological Association (APA) ,1962
- BRAIN INJURY, DRUGS, AND ENVIRONMENT AS CAUSES OF MENTAL DECAY IN EPILEPSYAmerican Journal of Psychiatry, 1942