Risk of SARS-CoV-2 exposure among hospital healthcare workers in relation to patient contact and type of care
Open Access
- 19 June 2021
- journal article
- research article
- Published by SAGE Publications in Scandinavian Journal of Public Health
- Vol. 49 (7), 707-712
- https://doi.org/10.1177/14034948211022434
Abstract
We aimed to assess prevalence of IgG antibodies to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and factors associated with seropositivity in a large cohort of healthcare workers (HCWs). From 11 May until 11 June 2020, 3981 HCWs at a large Swedish emergency care hospital provided serum samples and questionnaire data. Presence of IgG antibodies to SARS-CoV-2 was measured as an indicator of SARS-CoV-2 exposure. The total seroprevalence was 18% and increased during the study period. Among the seropositive HCWs, 11% had been entirely asymptomatic. Participants who worked with COVID-19 patients had higher odds for seropositivity: adjusted odds ratio 1.96 (95% confidence intervals 1.59–2.42). HCWs from three of the departments managing COVID-19 patients had significantly higher seroprevalences, whereas the prevalence among HCWs from the intensive care unit (also managing COVID-19 patients) was significantly lower. HCWs in contact with SARS-CoV-2 infected patients had a variable, but on average higher, likelihood for SARS-CoV-2 infections.Keywords
Funding Information
- Vetenskapsrådet
- Stockholms Läns Landsting
- Knut och Alice Wallenbergs Stiftelse
- Familjen Erling-Perssons Stiftelse
- Hjärt-Lungfonden
This publication has 10 references indexed in Scilit:
- Prevalence of comorbidity in Chinese patients with COVID-19: systematic review and meta-analysis of risk factorsBMC Infectious Diseases, 2021
- SARS-CoV-2 Transmission From People Without COVID-19 SymptomsJAMA Network Open, 2021
- Risk of COVID-19 in health-care workers in Denmark: an observational cohort studyThe Lancet Infectious Diseases, 2020
- Seroprevalence of SARS-CoV-2 antibodies and associated factors in healthcare workers: a systematic review and meta-analysisJournal of Hospital Infection, 2020
- SARS-CoV-2 exposure, symptoms and seroprevalence in healthcare workers in SwedenNature Communications, 2020
- Seroprevalence of SARS-CoV-2 Among Frontline Health Care Personnel in a Multistate Hospital Network — 13 Academic Medical Centers, April–June 2020MMWR. Morbidity and Mortality Weekly Report, 2020
- Prevalence of SARS-CoV-2 Antibodies in Health Care Personnel in the New York City AreaJama-Journal Of The American Medical Association, 2020
- Seroprevalence of SARS-CoV-2 antibodies in healthcare workers at a London NHS TrustInfection Control & Hospital Epidemiology, 2020
- Seroprevalence of SARS-CoV-2 Among Frontline Healthcare Personnel During the First Month of Caring for Patients With COVID-19—Nashville, TennesseeClinical Infectious Diseases, 2020
- Cryo-EM structure of the 2019-nCoV spike in the prefusion conformationScience, 2020