Models of Care for the Management of Hepatitis C Virus Among People Who Inject Drugs: One Size Does Not Fit All
Top Cited Papers
Open Access
- 15 August 2013
- journal article
- review article
- Published by Oxford University Press (OUP) in Clinical Infectious Diseases
- Vol. 57 (suppl_2), S56-S61
- https://doi.org/10.1093/cid/cit271
Abstract
One of the major obstacles to hepatitis C virus (HCV) care in people who inject drugs (PWID) is the lack of treatment settings that are suitably adapted for the needs of this vulnerable population. Nevertheless, HCV treatment has been delivered successfully to PWID through various multidisciplinary models such as community-based clinics, substance abuse treatment clinics, and specialized hospital-based clinics. Models may be integrated in primary care—all under one roof in either addiction care units or general practitioner–based models—or can occur in secondary or tertiary care settings. Additional innovative models include directly observed therapy and peer-based models. A high level of acceptance of the individual life circumstances of PWID rather than rigid exclusion criteria will determine the level of success of any model of HCV management. The impact of highly potent and well-tolerated interferon-free HCV treatment regimens will remain negligible as long as access to therapy cannot be expanded to the most affected risk groups.This publication has 50 references indexed in Scilit:
- Patients receiving opioid maintenance treatment in primary care: successful chronic hepatitis C care in a real world settingBMC Infectious Diseases, 2013
- A Randomized Controlled Trial of an Integrated Care Intervention to Increase Eligibility for Chronic Hepatitis C TreatmentThe American Journal of Gastroenterology, 2011
- Global epidemiology of hepatitis B and hepatitis C in people who inject drugs: results of systematic reviewsThe Lancet, 2011
- Barriers to Providing Health Services for HIV/AIDS, Hepatitis C Virus Infection and Sexually Transmitted Infections in Substance Abuse Treatment Programs in the United StatesJournal of Addictive Diseases, 2011
- Directly observed antiretroviral therapy improves adherence and viral load in drug users attending methadone maintenance clinics: A randomized controlled trialDrug and Alcohol Dependence, 2011
- Factors to Improve the Management of Hepatitis C in Drug Users: An Observational Study in an Addiction CentreGastroenterology Research and Practice, 2010
- Successful Integration of Hepatitis C Evaluation and Treatment Services With Methadone MaintenanceJournal of Addiction Medicine, 2010
- Factors associated with uptake of treatment for recent hepatitis C virus infection in a predominantly injecting drug user cohort: The ATAHC StudyDrug and Alcohol Dependence, 2010
- Successful treatment of chronic hepatitis C with pegylated interferon in combination with ribavirin in a methadone maintenance treatment programJournal of Substance Abuse Treatment, 2009
- Hepatitis C management by addiction medicine physicians: Results from a national surveyJournal of Substance Abuse Treatment, 2007