Mucocutaneous Angiomyolipoma
Open Access
- 1 September 1999
- journal article
- Published by Archives of Pathology and Laboratory Medicine in Archives of Pathology & Laboratory Medicine
- Vol. 123 (9), 789-792
- https://doi.org/10.5858/1999-123-0789-ma
Abstract
Objective.—Angiomyolipoma (AML) is a distinctive tumor that usually occurs in the kidney and rarely in the liver. Angiomyolipoma of other sites is extremely rare, and, to our knowledge, only 2 cases have been described in the nasal cavity. We present 2 additional cases of AML of the nasal cavity and discuss the difference between them and renal AML. Case Reports and Pathologic Findings.—Two tumors in a 66-year-old man and an 88-year-old woman without tuberous sclerosis are described. They showed 20-mm, well-circumscribed, polypoid shapes. Histologically, they were composed of mature smooth muscle cells, fat cells, and various-sized blood vessels. In addition, aggregated small lymphocytes were noted. Neither epithelioid smooth muscle cells nor HMB45 immunoreactivity was seen in either case. Conclusions.—The clinicopathologic features of AML of the nasal cavity are distinct from renal and hepatic AML and are common to those of AML arising in the skin and oral and pharyngeal mucosa. The term mucocutaneous angiomyolipoma is thought to be appropriate to express these characteristic tumors.Keywords
This publication has 23 references indexed in Scilit:
- Epithelioid Angiomyolipoma of the KidneyThe American Journal of Surgical Pathology, 1997
- Angiomyolipoma of the nasal cavity: Case report and review of the literatureHead & Neck, 1994
- Angiomyolipoma of the liver: A collective reviewThe Esophagus, 1994
- Cutaneous angiomyolipoma with pleomorphic changesJournal of the American Academy of Dermatology, 1993
- AngiomyolipomaJournal of the American Academy of Dermatology, 1992
- Cutaneous AngiomyolipomaThe American Journal of Dermatopathology, 1991
- Melanocyte-marker-HMB-45 is regularly expressed in angiomyolipoma of the kidneyPathology, 1991
- Hepatic Angiomyolipoma with Striated Granules and Positivity with Melanoma-Specific Antibody (HMB-45): A Report of Two CasesUltrastructural Pathology, 1991
- Cutaneous angiolipoleiomyomaJournal of the American Academy of Dermatology, 1990
- Angiomyolipoma of the vaginaGynecologic Oncology, 1990