Modeling the Occurrence of Mycobacterium avium subsp. paratuberculosis in Bulk Raw Milk and the Impact of Management Options for Exposure Mitigation
- 1 July 2011
- journal article
- Published by Elsevier BV in Journal of Food Protection
- Vol. 74 (7), 1126-1136
- https://doi.org/10.4315/0362-028x.jfp-11-005
Abstract
Mycobacterium avium subsp. paratuberculosis (MAP) is the causal agent of paratuberculosis (Johne's disease) in cattle and other farm ruminants. The potential role of MAP in Crohn's disease in humans and the contribution of dairy products to human exposure to MAP continue to be the subject of scientific debate. The occurrence of MAP in bulk raw milk from dairy herds was assessed using a stochastic modeling approach. Raw milk samples were collected from bulk tanks in dairy plants and tested for the presence of MAP. Results from this analytical screening were used in a Bayesian network to update the model prediction. Of the 83 raw milk samples tested, 4 were positive for MAP by culture and PCR. We estimated that the level of MAP in bulk tanks ranged from 0 CFU/ml for the 2.5th percentile to 65 CFU/ml for the 97.5th percentile, with 95% credibility intervals of [0, 0] and [16, 326], respectively. The model was used to evaluate the effect of measures aimed at reducing the occurrence of MAP in raw milk. Reducing the prevalence of paratuberculosis has less of an effect on the occurrence of MAP in bulk raw milk than does managing clinically infected animals through good farming practices.Keywords
This publication has 37 references indexed in Scilit:
- An inter-laboratory ring trial for the detection and isolation of Mycobacterium avium subsp. paratuberculosis from raw milk artificially contaminated with naturally infected faecesFood Microbiology, 2008
- Prevalence of serum antibodies to Mycobacterium avium subsp. paratuberculosis in cattle in Galicia (northwest Spain)Preventive Veterinary Medicine, 2007
- Assessment of the Prevalence ofMycobacterium aviumsubsp.paratuberculosisin Commercially Pasteurized MilkFoodborne Pathogens & Disease, 2007
- Reduction in milk yield associated withMycobacterium aviumsubspeciesparatuberculosis(Map) infection in dairy cowsVeterinary Research, 2007
- Guía de buenas prácticas ganaderas para la seguridad sanitaria de los alimentos derivados de la producción animalRevue Scientifique et Technique de l'OIE, 2006
- Detection of Viable Mycobacterium avium subsp. paratuberculosis in Retail Pasteurized Whole Milk by Two Culture Methods and PCRJournal of Food Protection, 2005
- Zoonotic aspects of Mycobacterium bovis and Mycobacterium avium-intracellulare complex (MAC)Veterinary Research, 2005
- Mycobacterium aviumSubspeciesparatuberculosisCultured from Locally and Commercially Pasteurized Cow's Milk in the Czech RepublicApplied and Environmental Microbiology, 2005
- Detection of Mycobacterium avium subspecies paratuberculosis specific IS900 insertion sequences in bulk-tank milk samples obtained from different regions throughout SwitzerlandBMC Microbiology, 2002
- Prevalence of paratuberculosis (Johne's disease) in the Belgian cattle populationVeterinary Microbiology, 2000