Beyond directed evolution—semi-rational protein engineering and design
Top Cited Papers
- 31 December 2010
- journal article
- review article
- Published by Elsevier BV in Current Opinion in Biotechnology
- Vol. 21 (6), 734-743
- https://doi.org/10.1016/j.copbio.2010.08.011
Abstract
No abstract availableKeywords
This publication has 39 references indexed in Scilit:
- Natural Diversity to Guide Focused Directed EvolutionChemBioChem, 2010
- Macromolecular Modeling with RosettaAnnual Review of Biochemistry, 2008
- Kemp elimination catalysts by computational enzyme designNature, 2008
- De Novo Computational Design of Retro-Aldol EnzymesScience, 2008
- A diverse family of thermostable cytochrome P450s created by recombination of stabilizing fragmentsNature Biotechnology, 2007
- Identification of fungal oxaloacetate hydrolyase within the isocitrate lyase/PEP mutase enzyme superfamily using a sequence marker-based methodProteins: Structure, Function, and Bioinformatics, 2007
- Engineering proteinase K using machine learning and synthetic genesBMC Biotechnology, 2007
- Structure-guided SCHEMA recombination of distantly related β-lactamases"Protein Engineering, Design and Selection", 2006
- Mechanism of enhanced conversion of 1,2,3-trichloropropane by mutant haloalkane dehalogenase revealed by molecular modelingJournal of Computer-Aided Molecular Design, 2006
- Structure-Guided Recombination Creates an Artificial Family of Cytochromes P450PLoS Biology, 2006