DNA analysis based on toehold-mediated strand displacement on graphene oxide
- 5 September 2013
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Chemical Communications
- Vol. 49 (86), 10139-10141
- https://doi.org/10.1039/c3cc45531a
Abstract
Fluorescent dye-labeled probe DNA was immobilized on fluorescence-quenching graphene oxide (GO) through a capture DNA. When targets were added, the probes were released from the GO through toehold-mediated strand exchange. Higher emission recovery and more signal contrast were achieved relative to conventional methods that are based on direct adsorption of probes.Keywords
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