Stereoselective Metabolism of Bupropion by Cytochrome P4502B6 (CYP2B6) and Human Liver Microsomes
- 25 January 2008
- journal article
- research article
- Published by Springer Science and Business Media LLC in Pharmaceutical Research
- Vol. 25 (6), 1405-1411
- https://doi.org/10.1007/s11095-008-9535-1
Abstract
No abstract availableKeywords
This publication has 39 references indexed in Scilit:
- Stereoselective Bupropion Hydroxylation as an In Vivo Phenotypic Probe for Cytochrome P4502B6 (CYP2B6) ActivityThe Journal of Clinical Pharmacology, 2008
- Stereoselective analysis of bupropion and hydroxybupropion in human plasma and urine by LC/MS/MSJournal of Chromatography B, 2007
- Identification of bupropion urinary metabolites by liquid chromatography/mass spectrometryRapid Communications in Mass Spectrometry, 2007
- Enantiomeric Metabolic Interactions and Stereoselective Human Methadone MetabolismJournal of Pharmacology and Experimental Therapeutics, 2007
- Stereoselective analysis of hydroxybupropion and application to drug interaction studiesChirality, 2006
- Bupropion for major depressive disorder: Pharmacokinetic and formulation considerationsClinical Therapeutics, 2005
- SELECTIVE INHIBITION OF CYP2B6-CATALYZED BUPROPION HYDROXYLATION IN HUMAN LIVER MICROSOMES IN VITRODrug Metabolism and Disposition, 2004
- Effect of bupropion on CYP2B6 and CYP3A4 catalytic activity, immunoreactive protein and mRNA levels in primary human hepatocytes: comparison with rifampicinJournal of Pharmacy and Pharmacology, 2003
- Smoking, alcoholism and genetic polymorphisms alter CYP2B6 levels in human brainNeuropharmacology, 2003
- Disposition of Bupropion in Healthy Volunteers andJournal of Clinical Psychopharmacology, 1990