Targeting the Insulin Growth Factor Receptor 1
- 30 June 2012
- journal article
- review article
- Published by Elsevier BV in Hematology/Oncology Clinics of North America
- Vol. 26 (3), 527-542
- https://doi.org/10.1016/j.hoc.2012.01.004
Abstract
No abstract availableKeywords
This publication has 124 references indexed in Scilit:
- Growth Hormone Receptor Deficiency Is Associated with a Major Reduction in Pro-Aging Signaling, Cancer, and Diabetes in HumansScience Translational Medicine, 2011
- Increased Insulin-Like Growth Factor 1 Receptor Protein Expression and Gene Copy Number in Small Cell Lung CancerJournal of Thoracic Oncology, 2010
- Wilms’ tumor 1 silencing decreases the viability and chemoresistance of glioblastoma cells in vitro: a potential role for IGF-1R de-repressionJournal of Neuro-Oncology, 2010
- Safety, pharmacokinetics, and preliminary activity of the anti-IGF-1R antibody figitumumab (CP-751,871) in patients with sarcoma and Ewing's sarcoma: a phase 1 expansion cohort studyThe Lancet Oncology, 2010
- Strong expression of IGF1R in pediatric gastrointestinal stromal tumors without IGF1R genomic amplificationInternational Journal of Cancer, 2010
- Chemoresistant Colorectal Cancer Cells, the Cancer Stem Cell Phenotype, and Increased Sensitivity to Insulin-like Growth Factor-I Receptor InhibitionCancer Research, 2009
- Insulin-like growth factor 1 receptor is a potential therapeutic target for gastrointestinal stromal tumorsProceedings of the National Academy of Sciences of the United States of America, 2008
- Characterization of insulin/IGF hybrid receptors: contributions of the insulin receptor L2 and Fn1 domains and the alternatively spliced exon 11 sequence to ligand binding and receptor activationBiochemical Journal, 2007
- Identification of IGF2 signaling through phosphoinositide-3-kinase regulatory subunit 3 as a growth-promoting axis in glioblastomaProceedings of the National Academy of Sciences of the United States of America, 2007
- Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/ neu OncogeneScience, 1987