Qualitative and Quantitative Analysis of Mycotoxins
Open Access
- 8 June 2009
- journal article
- Published by Wiley in Comprehensive Reviews in Food Science and Food Safety
- Vol. 8 (3), 202-251
- https://doi.org/10.1111/j.1541-4337.2009.00079.x
Abstract
Mycotoxin toxicity occurs at very low concentrations, therefore sensitive and reliable methods for their detection are required. Consequently, sampling and analysis of mycotoxins is of critical importance because failure to achieve a suitable verified analysis can lead to unacceptable consignments being accepted or satisfactory shipments unnecessarily rejected. The general mycotoxin analyses carried out in laboratories are still based on physicochemical methods, which are continually improved. Further research in mycotoxin analysis has been established in such techniques as screening methods with TLC, GC, HPLC, and LC–MS. In some areas of mycotoxin method development, immunoaffinity columns and multifunctional columns are good choices as cleanup methods. They are appropriate to displace conventional liquid–liquid partitioning or column chromatography cleanup. On the other hand, the need for rapid yes/no decisions for exported or imported products has led to a number of new screening methods, mainly, rapid and easy‐to‐use test kits based on immuno‐analytical principles. In view of the fact that analytical methods for detecting mycotoxins have become more prevalent, sensitive, and specific, surveillance of foods for mycotoxin contamination has become more commonplace. Reliability of methods and well‐defined performance characteristics are essential for method validation. This article covers some of the latest activities and progress in qualitative and quantitative mycotoxin analysis.Keywords
This publication has 111 references indexed in Scilit:
- Biomolecule-functionalized magnetic nanoparticles for flow-through quartz crystal microbalance immunoassay of aflatoxin B1Bioprocess and Biosystems Engineering, 2008
- Aflatoxins occurrence in milk and feed in Northern Italy during 2004–2005Food Control, 2007
- Analysis of Fusarium toxins in feedAnimal Feed Science and Technology, 2007
- Development and integration of an immunoaffinity monolithic disk for the on-line solid-phase extraction and HPLC determination with fluorescence detection of aflatoxin B1 in aqueous solutionsJournal of Pharmaceutical and Biomedical Analysis, 2007
- Natural occurrence of mycotoxins in cereals and spices commercialized in MoroccoFood Control, 2006
- Identification and quantification of mycotoxigenic fungi by PCRProcess Biochemistry, 2006
- Ochratoxin A determination in paired kidneys and muscle samples from swines slaughtered in southern ItalyFood Control, 2006
- Mycotoxins in food products available in QatarFood Control, 2004
- Biosensors and multiple mycotoxin analysisFood Control, 2003
- High-performance liquid chromatographic screening method for mycotoxins using new retention indexes and diode array detectionArchives of Environmental Contamination and Toxicology, 1989