Cancer of the ovary, fallopian tube, and peritoneum
Top Cited Papers
Open Access
- 30 September 2018
- journal article
- research article
- Published by Wiley in International Journal of Gynecology & Obstetrics
- Vol. 143 (S2), 59-78
- https://doi.org/10.1002/ijgo.12614
Abstract
The Gynecologic Oncology Committee of FIGO in 2014 revised the staging of ovarian cancer, incorporating ovarian, fallopian tube, and peritoneal cancer into the same system. Most of these malignancies are high-grade serous carcinomas (HGSC). Stage IC is now divided into three categories: IC1 (surgical spill); IC2 (capsule ruptured before surgery or tumor on ovarian or fallopian tube surface); and IC3 (malignant cells in the ascites or peritoneal washings). The updated staging includes a revision of Stage IIIC based on spread to the retroperitoneal lymph nodes alone without intraperitoneal dissemination. This category is now subdivided into IIIA1(i) (metastasis <= 10 mm in greatest dimension), and IIIA1(ii) (metastasis >10 mm in greatest dimension). Stage IIIA2 is now microscopic extrapelvic peritoneal involvement with or without positive retroperitoneal lymph node metastasis. This review summarizes the genetics, surgical management, chemotherapy, and targeted therapies for epithelial cancers, and the treatment of ovarian germ cell and stromal malignancies.This publication has 140 references indexed in Scilit:
- Assessment of symptomatic women for early diagnosis of ovarian cancer: results from the prospective DOvE pilot projectThe Lancet Oncology, 2012
- Mutations in 12 genes for inherited ovarian, fallopian tube, and peritoneal carcinoma identified by massively parallel sequencingProceedings of the National Academy of Sciences of the United States of America, 2011
- Clinical Trials in Recurrent Ovarian CancerInternational Journal of Gynecologic Cancer, 2011
- Histological response is not a prognostic factor after neoadjuvant chemotherapy in advanced-stage ovarian cancer with no residual diseaseEuropean Journal of Obstetrics & Gynecology and Reproductive Biology, 2009
- Defining the Cut Point Between Low-grade and High-grade Ovarian Serous CarcinomasThe American Journal of Surgical Pathology, 2009
- Serous Tubal Intraepithelial Carcinoma: Its Potential Role in Primary Peritoneal Serous Carcinoma and Serous Cancer PreventionJournal of Clinical Oncology, 2008
- Pathogenesis of Ovarian CancerInternational Journal of Gynecological Pathology, 2008
- Symptoms associated with diagnosis of ovarian cancer: a systematic reviewBJOG: An International Journal of Obstetrics and Gynaecology, 2005
- The Risk of Cancer Associated with Specific Mutations ofBRCA1andBRCA2among Ashkenazi JewsThe New England Journal of Medicine, 1997
- Cyclophosphamide and Cisplatin Compared with Paclitaxel and Cisplatin in Patients with Stage III and Stage IV Ovarian CancerThe New England Journal of Medicine, 1996