Genipin inhibits UCP2-mediated proton leak and acutely reverses obesity- and high glucose-induced β cell dysfunction in isolated pancreatic islets
- 1 June 2006
- journal article
- research article
- Published by Elsevier BV in Cell Metabolism
- Vol. 3 (6), 417-427
- https://doi.org/10.1016/j.cmet.2006.04.010
Abstract
No abstract availableKeywords
This publication has 32 references indexed in Scilit:
- A signalling role for 4-hydroxy-2-nonenal in regulation of mitochondrial uncouplingThe EMBO Journal, 2003
- Superoxide activates mitochondrial uncoupling proteinsNature, 2002
- Increased Uncoupling Protein-2 Levels in β-cells Are Associated With Impaired Glucose-Stimulated Insulin SecretionDiabetes, 2001
- Uncoupling proteins 2 and 3 are highly active H + transporters and highly nucleotide sensitive when activated by coenzyme Q (ubiquinone)Proceedings of the National Academy of Sciences, 2001
- Glucose-induced [Ca2+]i abnormalities in human pancreatic islets: important role of overstimulation.Diabetes, 2000
- Biocompatibility study of a biological tissue fixed with a naturally occurring crosslinking reagentJournal of Biomedical Materials Research, 1998
- Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemiaNature Genetics, 1997
- Genipin, a new type of protein crosslinking reagent from gardenia fruits.Agricultural and Biological Chemistry, 1988
- Structure of genipocyanin G1, a spontaneous reaction product between genipin and glycineTetrahedron Letters, 1987
- Terpenoids. XLVII.1 The Structure of Genipin2The Journal of Organic Chemistry, 1961