Regulation of natural killer activityin vivo. II. The effect of alcohol consumption on human peripheral blood natural killer activity
- 15 October 1980
- journal article
- research article
- Published by Wiley in International Journal of Cancer
- Vol. 26 (4), 413-417
- https://doi.org/10.1002/ijc.2910260405
Abstract
Natural killer (NK) activity of human peripheral blood lymphocytes (HPBL) was studied in 32 alcoholics and 15 control subjects in a 4-h chromium release assay using K562 tumor target cells. The natural killer activity of human peripheral blood lymphocytes in alcoholics was significantly higher than the level found in the control group. NK activity of PBL from alcoholics was still higher than that of similarly treated PBL from control subjects after carbonyl iron and magnet treatment, or after passage through a nylon wool column or after removal of cells rosetting with sheep erythrocytes. Changes in T cell, B cell or macrophage populations, therefore, are not the mechanism for increased NK activity in alcoholics.This publication has 15 references indexed in Scilit:
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