Prognostic significance of morphologic parameters in renal cell carcinoma
- 29 April 2004
- journal article
- Published by Hindawi Limited in International Journal of Clinical Practice
- Vol. 58 (4), 333-336
- https://doi.org/10.1111/j.1368-5031.2004.00008.x
Abstract
Many morphologic parameters have been used in prognostic studies in renal cell carcinoma. In this study, the relationship between these parameters and prognosis was investigated. This study includes 75 patients who were treated with radical nephrectomy between 1985 and 2001. Pathological stage (TNM), grade (Fuhrman nuclear grade) cell type (UICC and AJCC), histologic pattern, tumour size, vascular invasion and multifocality were used as prognostic parameters. There were 34 female and 41 male patients with mean age of 54.5 ± 12.5. The mean size of the tumour was 76.9 ± 37.2 (30–200) mm. Of the patients, 40 had pT1, 21 pT2, nine pT3 and two pT4 diseases. Twenty‐eight patients had Grade 1, 29 Grade 2, 15 Grade 3 and three Grade 4 tumour. According to cell type, 63 had clear cell, six papillary and six undifferentiated types. Five had multifocal and seven had vascular invasion. In conclusion, nuclear grade and tumour stage were found as the most important prognostic indicators.Keywords
This publication has 16 references indexed in Scilit:
- INFLUENCE OF TUMOR STAGE, SIZE, GRADE, VASCULAR INVOLVEMENT, HISTOLOGICAL CELL TYPE AND HISTOLOGICAL PATTERN ON MULTIFOCALITY OF RENAL CELL CARCINOMAJournal of Urology, 2000
- Nuclear morphometry adds significant prognostic information to stage and grade for renal cell carcinomaUrology, 1999
- Volume-weighted mean nuclear volume in renal cell carcinomaUrology, 1998
- TNM staging of renal cell carcinomaCancer, 1997
- Radical Nephrectomy for Renal Cell Carcinoma: Long-Term Results and Prognostic Factors on a Series of 328 CasesEuropean Urology, 1997
- Renal cell carcinoma II. Histological indicators of prognosisPathology, 1987
- Histopathology and Classification of Renal Cell Tumors (Adenomas, Oncocytomas and Carcinomas): The Basic Cytological and Histopathological Elements and their Use for DiagnosticsPathology - Research and Practice, 1986
- Prognostic significance of morphologic parameters in renal cell carcinomaThe American Journal of Surgical Pathology, 1982
- Diagnosis and management of renal cell carcinomaA clinical and pathologic study of 309 casesCancer, 1971
- The Results of Radical Nephrectomy for Renal Cell CarcinomaJournal of Urology, 1969