Wavefront-guided laser in situ keratomileusis using the WaveScan system for correction of low to moderate myopia with astigmatism: 6-month results in 277 eyes

Abstract

To assess the safety and effectiveness of wavefront guided LASIK surgery using the Visx WaveScan system for correction of low to moderate myopia with astigmatism. Multicenter study at 6 sites in the United States. In this prospective nonrandomized clinical trial, treatments were performed at 6 sites in the United States using the WaveScan (CustomVue) guided excimer laser. A total of 351 eyes were enrolled, and 277 eyes were analyzed at 6 months. At 6 months, 94% of eyes achieved an uncorrected visual acuity (UCVA) of 20/20 or better and 74% achieved a UCVA of 20/16 or better. Sixty-nine percent of eyes had the same or better postoperative UCVA than their preoperative best spectacle-corrected visual acuity (BSCVA). Ninety percent of eyes were within +/-0.5 diopter of intended correction. No eye lost more than 1 line of BSCVA. Total higher-order root-mean square (RMS), coma, and spherical aberration values were stable (P<.05). The data support the safety and effectiveness of the WaveScan-guided customized laser ablation using the Visx Star S4 system for correction of low to moderate myopia with astigmatism.