HCLK2 Is Required for Activity of the DNA Damage Response Kinase ATR
Open Access
- 1 February 2009
- journal article
- Published by Elsevier BV
- Vol. 284 (7), 4140-4147
- https://doi.org/10.1074/jbc.m808174200
Abstract
No abstract availableKeywords
This publication has 35 references indexed in Scilit:
- TopBP1 activates ATR through ATRIP and a PIKK regulatory domainGenes & Development, 2008
- Tel2 mediates activation and localization of ATM/Tel1 kinase to a double-strand breakGenes & Development, 2008
- Rapamycin sensitivity of the Schizosaccharomyces pombe tor2 mutant and organization of two highly phosphorylated TOR complexes by specific and common subunitsGenes to Cells, 2007
- Claspin Operates Downstream of TopBP1 To Direct ATR Signaling towards Chk1 ActivationMolecular and Cellular Biology, 2006
- Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaksThe Journal of cell biology, 2006
- Identification and functional analysis of TopBP1 and its homologsDNA Repair, 2005
- Dynamic assembly and sustained retention of 53BP1 at the sites of DNA damage are controlled by Mdc1/NFBD1The Journal of cell biology, 2005
- Claspin and the Activated Form of ATR-ATRIP Collaborate in the Activation of Chk1Published by Elsevier BV ,2004
- DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociationNature, 2003
- The DNA damage-dependent intra–S phase checkpoint is regulated by parallel pathwaysNature Genetics, 2002