Phagocytosis reduces HIV-1 production in human monocytes/macrophages infected in vitro
- 1 September 1993
- journal article
- Published by Springer Science and Business Media LLC in Archiv für die gesamte Virusforschung
- Vol. 130 (3-4), 463-469
- https://doi.org/10.1007/bf01309674
Abstract
The addition of ingestible particles (opsonized erythrocytes or latex beads) or a phorbol ester activates monocytes — derived human macrophages (MDHM) cultured in vitro, and markedly reduces virion release from HIV-infected MDHM as well as their ability to transmit the infection to cocultured lymphoid CD 4-positive CEM cells.Keywords
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