The Significance of Bladder Quadrant Biopsies in Patients with Primary Superficial Bladder Carcinoma
- 1 January 1989
- journal article
- research article
- Published by Elsevier BV in European Urology
- Vol. 16 (2), 81-85
- https://doi.org/10.1159/000471541
Abstract
The prognostic significance of dysplasia (D I-III, Tis) based on bladder quadrant biopsies was established in 216 patients with primary urothelial carcinoma of the bladder (stage pTaGI-pTGIII). Collectively within the study, 51 of the 216 patients biopsied (24%) were found with abnormal urothelium. Twelve (6%) have coexistent Tis, and 30 (18%) were found with dysplastic changes DI-III. Further concerns included the incidence of dysplastic changes associated with tumor invasion, tumor dedifferentiation, and the presence of primary multifocal disease. The collective recurrence rate was 43%. However, with inclusion of quadrant biopsies, the predictability of positive biopsy results increased to 63% and the negative rate decreased to 37%.This publication has 13 references indexed in Scilit:
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