Invasive micropapillary carcinoma of the breast had poor clinical characteristics but showed no difference in prognosis compared with invasive ductal carcinoma
Open Access
- 5 August 2016
- journal article
- research article
- Published by Springer Science and Business Media LLC in World Journal of Surgical Oncology
- Vol. 14 (1), 1-7
- https://doi.org/10.1186/s12957-016-0960-z
Abstract
It is controversial for prognosis of invasive micropapillary carcinoma (IMPC) compared with invasive ductal carcinoma (IDC) of the breast. To better understand the difference between IMPC and IDC prognoses, we conducted this retrospective study. Data from 33 patients with IMPC were retrospectively reviewed, and the clinicopathologic characteristics and survival status were compared with those of 347 patients with IDC who were treated during the same period. The IMPC cases were of larger tumor size, greater proportion of nodal involvement, and an increased incidence of lymphovascular invasion compared with IDC cases. The overall survival (OS), local relapse-free survival (LRFS), distant metastasis-free survival (DMFS), and failure-free survival (FFS) rates were not significantly different between IMPC and IDC. The 3-year OS rate was 97 vs 94.2 % for the IMPC and IDC patients, respectively. The 3-year FFS rate was 87.9 vs 86.2 % for the IMPC and IDC patients, respectively. For IMPC patients, the 3-year LRFS rate was 93.9 % and in IDC patients was 89.0 %. The 3-year DMFS rates of IMPC patients was 90.9 % and IDC patients was 89 %. IMPC had poor clinical characteristics, but it showed no difference in OS, FFS, LRFS, and DMFS compare with IDC.Keywords
Funding Information
- Hainan Province Natural Science Funding (20158293)
- Hainan Province Medical and Health Research Project (200309)
This publication has 18 references indexed in Scilit:
- Inner nuclear membrane localization of epidermal growth factor receptor (EGFR) in spontaneous canine model of invasive micropapillary carcinoma of the mammary glandPathology - Research and Practice, 2016
- Similar Prognoses for Invasive Micropapillary Breast Carcinoma and Pure Invasive Ductal Carcinoma: A Retrospectively Matched Cohort Study in ChinaPLOS ONE, 2014
- Population-based comparison of prognostic factors in invasive micropapillary and invasive ductal carcinoma of the breastBritish Journal of Cancer, 2014
- Current Approaches and Challenges in Monitoring Treatment Responses in Breast CancerJournal of Cancer, 2014
- Invasive Micropapillary Carcinoma of the Breast: A Clinicopathologic Study of 103 Cases of an Unusual and Highly Aggressive Variant of Breast CarcinomaThe Breast Journal, 2013
- Prognostic Markers for Invasive Micropapillary Carcinoma of the Breast: A Population-Based AnalysisClinical Breast Cancer, 2013
- The Global Breast Cancer BurdenFuture Oncology, 2012
- Clinical and pathologic features of invasive micropapillary carcinomaBreast Cancer, 2004
- [WHO classification of breast tumors and tumors of the female genital organs: pathology and genetics].2002
- Invasive micropapillary carcinoma of the breast.1993