Androgen Modulation of Adrenal Angiotensin Receptors
- 1 June 1984
- journal article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 224 (4652), 1009-1011
- https://doi.org/10.1126/science.6326265
Abstract
Several polar androgens increased the binding of angiotensin and its stimulation of aldosteronogenesis in bovine adrenal glomerulosa cells. The effect was seen only if the steroids were applied to the cells and then washed away. This phenomenon and the technique for demonstrating it may have implications for studies of receptor modulation and for clinical states in which responsiveness to angiotensin is increased.Keywords
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