Risk factors associated with bacteriological cure, new infection, and incidence of clinical mastitis after dry cow therapy with three different antibiotics
Open Access
- 1 January 2011
- journal article
- Published by The Korean Society of Veterinary Science in Journal of Veterinary Science
- Vol. 12 (3), 227-233
- https://doi.org/10.4142/jvs.2011.12.3.227
Abstract
Factors affecting bacteriological cure rates (BCR) and new intramammary infections (IMI) during the dry period as well as clinical mastitis (CM) during early lactation were investigated in 414 German Holstein dairy cows receiving dry cow therapy. Cows were treated with either benethamine benzylpenicillin (300,000 IU), penethamate hydriodide (100,000 IU), and framycetin sulphate (100 mg, n = 136), or cefquinome (150 mg, n = 135), or benzathine cloxacillin (1,280 mg, n = 143). Overall BCR, IMI, and CM at parturition were 86.4%, 20.7%, and 4.3%, respectively. The three antibiotic treatments differed only in BCR, with cloxacillin yielding better results than the others. Udder quarters from cows with > 4 lactations had a higher risk of IMI and CM at calving. Chronic changes in udder tissues were linked to a lower BCR and were associated with a higher risk of CM during early lactation. The risk of CM at calving was higher in udder quarters with unspecific or subclinical mastitis before drying off. In conclusion, with antibiotic dry cow therapy, age and health status of the udder appear to be major determinants of IMI and CM during the dry period and early lactation, while BCR was associated with the antibiotic type and udder tissue status.Keywords
This publication has 21 references indexed in Scilit:
- Meta-analysis of dry cow management for dairy cattle. Part 2. Cure of existing intramammary infectionsJournal of Dairy Science, 2009
- Meta-analysis of dry cow management for dairy cattle. Part 1. Protection against new intramammary infectionsJournal of Dairy Science, 2009
- Factors affecting cure when treating bovine clinical mastitis with cephalosporin-based intramammary preparationsJournal of Dairy Science, 2009
- Cow, Farm, and Herd Management Factors in the Dry Period Associated with Raised Somatic Cell Counts in Early LactationJournal of Dairy Science, 2008
- Comparison of Feeding Management and Body Condition of Dairy Cows in Herds with Low and High Mastitis RatesJournal of Dairy Science, 2007
- Cow, Farm, and Management Factors During the Dry Period that Determine the Rate of Clinical Mastitis After CalvingJournal of Dairy Science, 2007
- Variation in the composition of selected milk fraction samples from healthy and mastitic quarters, and its significance for mastitis diagnosisJournal of Dairy Research, 2005
- Association of cow and quarter-level factors at drying-off with new intramammary infections during the dry periodPreventive Veterinary Medicine, 2004
- Classification and Longitudinal Examination of Callused Teat Ends in Dairy CowsJournal of Dairy Science, 2000
- Strategies for mastitis control: dry cow therapy and cullingAustralian Veterinary Journal, 1994