Metformin selectively attenuates mitochondrial H2O2 emission without affecting respiratory capacity in skeletal muscle of obese rats
- 15 September 2010
- journal article
- Published by Elsevier BV in Free Radical Biology & Medicine
- Vol. 49 (6), 1082-1087
- https://doi.org/10.1016/j.freeradbiomed.2010.06.022
Abstract
No abstract availableKeywords
This publication has 37 references indexed in Scilit:
- What is the mitochondrial permeability transition pore?Journal of Molecular and Cellular Cardiology, 2009
- Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humansJCI Insight, 2009
- Induction of Endogenous Uncoupling Protein 3 Suppresses Mitochondrial Oxidant Emission during Fatty Acid-supported RespirationPublished by Elsevier BV ,2007
- Type II skeletal myofibers possess unique properties that potentiate mitochondrial H2O2generationAmerican Journal of Physiology-Cell Physiology, 2006
- Metformin delays the manifestation of diabetes and vascular dysfunction in Goto–Kakizaki rats by reduction of mitochondrial oxidative stressDiabetes/Metabolism Research and Reviews, 2006
- High-fat diet feeding impairs both the expression and activity of AMPKa in rats’ skeletal muscleBiochemical and Biophysical Research Communications, 2006
- Metformin inhibits mitochondrial permeability transition and cell death: a pharmacological in vitro studyBiochemical Journal, 2004
- Role of AMP-activated protein kinase in mechanism of metformin actionJCI Insight, 2001
- Clinical Pharmacokinetics of MetforminClinical Pharmacokinetics, 1996
- Metformin improves peripheral but not hepatic insulin action in obese patients with type II diabetesActa Endocrinologica, 1989