Surgical outcome of solid pseudopapillary tumor of the pancreas
- 1 May 2008
- journal article
- Published by Springer Science and Business Media LLC in Journal of Hepato-Biliary-Pancreatic Surgery
- Vol. 15 (3), 318-321
- https://doi.org/10.1007/s00534-007-1264-z
Abstract
The best surgical treatment for solid pseudopapillary tumor of the pancreas is a matter of debate. Fourteen patients with solid pseudopapillary tumor of the pancreas who underwent surgical resection, including enucleation, between June 1996 and January 2007 were retrospectively analyzed to evaluate the effect of the treatment. The mean age of the patients was 39 years (range, 15 to 59 years). The mean size of the tumor was 4.4 cm (range, 2.0 to 12 cm). Ten tumors (71%) had a well-defined capsule, and 6 tumors (43%) extended beyond the pancreas. Eight of the 14 tumors (57%) had a cystic component, and calcification was observed in 6 tumors (43%). The frequency of microscopic venous invasion, lymphatic invasion, and nerve invasion was 29% (4 of 14), 0%, and 21% (3 of 14), respectively. No lymph node involvement or liver metastasis was observed. Six patients underwent positron emission tomography with 2-deoxy-2-[18F] fluoro-D-glucose (FDG), and stronger FDG accumulation compared with the surrounding pancreatic parenchyma was observed in 5 of the 6 patients. The median standardized uptake value (SUV) was 6.3 (range, 0.9 to 42.8). Distal pancreatectomy (n = 5), subtotal stomach-preserving pancreatoduodenectomy (n = 3), local resection (n = 3), enucleation (n = 2), and duodenum-preserving pancreatic head resection (n = 1) were performed. Overall morbidity and mortality rates were 43% and 0%, respectively. All patients were still alive without recurrent disease after a median follow-up of 46 months. Patients with solid pseudopapillary tumor of the pancreas had a favorable outcome after surgical treatment, including enucleation.This publication has 10 references indexed in Scilit:
- Treatment of liver metastases from a solid pseudopapillary tumor of the pancreasJournal of Hepato-Biliary-Pancreatic Surgery, 2006
- The use of standardized uptake values for assessing FDG uptake with PET in oncology: a clinical perspectiveNuclear Medicine Communications, 2004
- Urgent Whipple resection for solid pseudopapillary tumor of the pancreasJournal of Hepato-Biliary-Pancreatic Surgery, 2003
- Diagnosis of pancreatic cancer using fluorine-18 fluorodeoxyglucose positron emission tomography (FDG PET) —Usefulness and limitations in “clinical reality”—Annals of Nuclear Medicine, 2003
- Solid cystic tumor of the pancreas: report of six cases and a review of the Japanese literatureThe Esophagus, 2002
- Solid-pseudopapillary tumor of the pancreas: A surgical enigma?Annals of Surgical Oncology, 2002
- Solid and Papillary Epithelial Neoplasms of the Pancreas: Aggressive Resection for CureThe American Surgeon, 2001
- Diagnostic usefulness of FDG PET for pancreatic mass lesionsAnnals of Nuclear Medicine, 2001
- Solid-pseudopapillary tumor of the pancreas--a rare and frequently misdiagnosed neoplasm.Langenbecks Archives Of Surgery, 1999
- Operative Management of Papillary Cystic Neoplasms of the PancreasJournal of the American College of Surgeons, 1998