Effects of continuous estrogen and estrogen-progestin replacement regimens on cardiovascular risk markers in postmenopausal women.
Open Access
- 27 November 2000
- journal article
- clinical trial
- Published by American Medical Association (AMA) in Archives of Internal Medicine
- Vol. 160 (21), 3315-3325
- https://doi.org/10.1001/archinte.160.21.3315
Abstract
THE BENEFICIAL effects of estrogen use in postmenopausal women for management of estrogen deficiency symptoms and prevention of bone loss have been widely documented.1,2 The addition of a progestin, especially in a continuous manner, has been shown to reduce the risk of endometrial cancer associated with unopposed estrogen use in women with an intact uterus.3-5Keywords
This publication has 27 references indexed in Scilit:
- Randomized Trial of Estrogen Plus Progestin for Secondary Prevention of Coronary Heart Disease in Postmenopausal WomenJAMA, 1998
- Norethindrone Acetate Enhances the Antiatherogenic Effect of 17β-EstradiolArteriosclerosis, Thrombosis, and Vascular Biology, 1998
- Effects of Raloxifene on Serum Lipids and Coagulation Factors in Healthy Postmenopausal WomenJAMA, 1998
- Low-dose esterified estrogen therapy: effects on bone, plasma estradiol concentrations, endometrium, and lipid levels. Estratab/Osteoporosis Study GroupArchives of Internal Medicine, 1997
- Postmenopausal Hormone Therapy and MortalityNew England Journal of Medicine, 1997
- Hormone Therapy To Prevent Disease and Prolong Life in Postmenopausal WomenAnnals of Internal Medicine, 1992
- Progestogens do not affect aortic accumulation of cholesterol in ovariectomized cholesterol-fed rabbits.Circulation Research, 1992
- Effects of Postmenopausal Estrogen Replacement on the Concentrations and Metabolism of Plasma LipoproteinsNew England Journal of Medicine, 1991
- Estrogen replacement therapy and coronary heart disease: A quantitative assessment of the epidemiologic evidencePreventive Medicine, 1991
- Risk of endometrial cancer after treatment with oestrogens alone or in conjunction with progestogens: results of a prospective study.BMJ, 1989